Posts

Showing posts from June, 2020

CD4 Counts and Opportunistic Infections

Hello! >500/mm3 - Candidal vaginitis Persistent Generalized lymphadenopathy 200-500/mm3 - Pneumococcal pneumonia Pulmonary TB Herpes Zoster Oropharyngeal Candidiasis (Thrush) <200/mm3- Pneumocystis jiroveci pneumonia Miliary/Extrapulmonary TB <100/mm3- Candida Esophagitis Penicillinosis Toxoplasmosis Cryptococcosis <50/mm3- Mycobacterium avium coplex(MAC) Disseminated cytomegalovirus (CMV) Hope this will help. -Upasana Y.

Random must-to-know

Image
Hell o! I)Serologic markers of hepatic fibrosis can broadly be categorized as indirect or direct:   ●Indirect markers reflect alterations in hepatic function, but do not directly reflect extracellular matrix metabolism. Examples include the platelet count, coagulation studies, and liver aminotransferases. ●Direct markers of fibrosis reflect extracellular matrix turnover. Examples include procollagen types I and III, hylauronic acid , and tissue inhibitor of metalloproteinase . II)Permissive role of hormone- It means that the hormone enhances the action of another hormone. LEPTIN- It has an important permissive role in the progression into puberty and the maintenance of normal hypothalamic-pituitary-gonadal function. KISSPEPTIN- It is a principle activator of GnRH neurons and is a pre-requisite for the onset of puberty and maintenance of normal reproductive function. It is a neuropeptide. Loss of function mumtation of kisspeptin receptor gene (KISS1R) ...

How to make a revision plan?

Image
Hello! Today I will be sharing with you my revision plan. You can customize it according to your need and schedule. 1.Complete your first reading from notes. 2.I wanted to complete DVT, highlighted points in TND notes and Revise specific topic in some subject. Last few days I divided days into 3 slots (1st slot I read subjects I was scoring not so well, 2nd slot I wanted to complete previous year neet papers and Qbanks and 3rd slot notes and highlighted point from other subject. After giving mock or any test I make this pages for each subject to note down topics I want to review. Happy Studying! -Upasana Y. 

CHA2DS2VASc Score

Image
Hello ! You all must be familiar with the complications of atrial fibrillation (AF). The management of atrial fibrillation is centered on these complications. Thromboembolism is caused by AF. CHA2DS2VASc score is to estimate stroke risk in AF patients and to start OACs (oral anticoagulants). Previously, we have CHADS2 Score. Hope it will help. -Upasana Y. 

HMG CoA synthase,reductase and lyase

Image
Hello! This is one of the confuser in the options. Let me help you out with this. Have a great day. -Upasana Y.

Relative risk of invasive breast carcinoma based on histological examination

Hello! Based on histological examination of benign breast tissue, we can assess the relative risk of invasive breast carcinoma. Why do we want to assess this? In some studies it has been found that histologic features, the age at biopsy, and the degree of family history are major determinants of the risk of breast cancer after the diagnosis of benign breast disease.  1. Findings suggestive of  No increased risk -Adenosis (sclerosing or fibroid) -Cystic (macro & /micro) -Duct ectasia -Fibrosis -Fibroadenoma -hyperplasia -Mastitis -Squamous metaplasia -Periductal Mastitis 2. Findings suggestive of  slightly increased risk (1.5 to 2 times) -Hyperplasia, moderate or florid, solid or papillary -papilloma with fibrovascular core 3. Finding suggestive of  moderately increased risk  (5 times) -Atypical hyperplasia, ductal or lobular 4. Insufficient data to assign a risk -solitary papilloma of lactiferous sinus -Radical scar Lesi...

Neural crest cells (Clinical aspect)

Hello! :D Let us go back to  the contribution of neural crest cells to many different systems (neural, skin, teeth, head, face, heart, adrenal glands, and gastrointestinal tract). Neural crest forms neural and non-neural population. -Cranial neural crest -cardiac neural crest -trunk neural crest -Vagal neural crest So, Malformations of NC origin -Facial clefts, ear malformations, and other Facial defects  -Branchial fistulae and anomalies of pharyngeal arch derivatives -Cardiovascular malformations  -Pigmentary disorders -Abnormal enteric innervation  -Tumors  -Hemangiomas and vascular malformations 1. Facial clefts, ear malformations, and other facial defects-   The shaping of the face is therefore patterned under the influence of the NC. The more common malformations of the region -preauricular tags -microtia -cleft lip, and cleft palate -CHARGE association -Treacher Collins, or Goldenhar syndrome. 2...

Spherocytes

Hello ! Q. On peripheral blood smears there is presence of  spherocytes . What are the differentials and the test to identify the same? Most of you have prompted it as hereditary spherocytosis.  Let see. Ans.  DIFFERENTIALS :-  HEREDITARY SPHEROCYTOSIS AUTO-IMMUNE HEMOLYTIC ANEMIA  Best next step is to do  DIRECT COOMBS TEST  to rule out autoimmune hemolytic anemia. For hereditary spherocytosis go for osmotic fragility test.     So spherocytosis doesn't means Hereditary, it could be acquired, usually preceded by an infection. HAPPY STUDYING :)  - Upasana Y.

Aneuploidy screening

Image
Hello! Here is Last minute revision for aneuploidy screening in Obs Gynae. Happy Studying! -Upasana Y. 

Surgical blades, Cautery and Sepsis

Image
Hello! Here is Last minute revision post on tumor markers, Surgical blades, Cautery and sepsis. Hope it will help. -Upasana Y.