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Showing posts with the label NEET PG

CD4 Counts and Opportunistic Infections

Hello! >500/mm3 - Candidal vaginitis Persistent Generalized lymphadenopathy 200-500/mm3 - Pneumococcal pneumonia Pulmonary TB Herpes Zoster Oropharyngeal Candidiasis (Thrush) <200/mm3- Pneumocystis jiroveci pneumonia Miliary/Extrapulmonary TB <100/mm3- Candida Esophagitis Penicillinosis Toxoplasmosis Cryptococcosis <50/mm3- Mycobacterium avium coplex(MAC) Disseminated cytomegalovirus (CMV) Hope this will help. -Upasana Y.

Random must-to-know

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Hell o! I)Serologic markers of hepatic fibrosis can broadly be categorized as indirect or direct:   ●Indirect markers reflect alterations in hepatic function, but do not directly reflect extracellular matrix metabolism. Examples include the platelet count, coagulation studies, and liver aminotransferases. ●Direct markers of fibrosis reflect extracellular matrix turnover. Examples include procollagen types I and III, hylauronic acid , and tissue inhibitor of metalloproteinase . II)Permissive role of hormone- It means that the hormone enhances the action of another hormone. LEPTIN- It has an important permissive role in the progression into puberty and the maintenance of normal hypothalamic-pituitary-gonadal function. KISSPEPTIN- It is a principle activator of GnRH neurons and is a pre-requisite for the onset of puberty and maintenance of normal reproductive function. It is a neuropeptide. Loss of function mumtation of kisspeptin receptor gene (KISS1R) ...

Spherocytes

Hello ! Q. On peripheral blood smears there is presence of  spherocytes . What are the differentials and the test to identify the same? Most of you have prompted it as hereditary spherocytosis.  Let see. Ans.  DIFFERENTIALS :-  HEREDITARY SPHEROCYTOSIS AUTO-IMMUNE HEMOLYTIC ANEMIA  Best next step is to do  DIRECT COOMBS TEST  to rule out autoimmune hemolytic anemia. For hereditary spherocytosis go for osmotic fragility test.     So spherocytosis doesn't means Hereditary, it could be acquired, usually preceded by an infection. HAPPY STUDYING :)  - Upasana Y.

Vitamins high yield points.

Hello! :) I have never studied vitamin in this way .These were the questions asked during my pharmacology vivas. And I found it fascinating after studying. Q. Which vitamin deficiency is related with lowering of seizure threshold? Ans. Pyridoxine Vit B6 . As it is associated with synthesis of neurotransmitter GABA . Therefore it is indicated during Isoniazid induced convulsions. :) Q. Why laropiprant (20mg) + Niacin (1g) is used in combination? Ans. We know that here the main reason is nicotinic acid (a derivative)  which results in flushing of face. Why? Vasodilation of  cutaneous vessels. So we combine it with specific anti-flushing drug called laropiprant. Q .In hyperemesis gravidarum,what you give for associated Wernicke's encephalopathy following hyperemesis ? Ans. Even I thought of anti-emetics but it came out to be "vitamin B1" . (Everytime Wernicke's encephalopathy doesn't result from alcohol:P) That's for today. Take care. :) -Upy...