Thymic Cysts vs Other Anterior Mediastinal Lesions: Imaging Clues Every Radiology Resident Should Know
Hello Glias ! The anterior mediastinum is home to some of the most commonly encountered masses on chest imaging. Thymic cysts are benign, fluid-filled lesions but can easily be mistaken for neoplastic processes like thymoma, germ cell tumors, or lymphoma. Accurate differentiation avoids unnecessary surgeries and anxiety. What Are Thymic Cysts • Benign lesions arising in the thymus or thymopharyngeal tract • Uni- or multilocular • Can be congenital or acquired (infection, radiation, autoimmune disease) They frequently appear during an evaluation for unrelated symptoms or cancer staging. CT Clues On CT, a thymic cyst typically shows fluid attenuation , meaning it appears near water density. Some cysts may look slightly denser if they contain protein or blood products, but they still lack soft tissue nodularity. A true cyst shows no internal enhancement . At most, you may see a very thin enhancing rim corresponding to the capsule. If any mural nodularity or solid enhancin...