Organoids: Game changer

This is a brief article on current interesting research area that will revolutionize transplant field. 

Organoids- 

A self-organizing three-dimensional tissue known as an organoid is usually created from pluripotent, fetal, or adult stem cells. It replicates the essential biological, structural, and functional elements of an organ. Organoids are made up of cells that have been produced from tissue-derived cells (TDCs), induced pluripotent stem cells (iPSCs), differentiated cells, and cancer cells. Organoid cultures, in contrast to traditional 2D cultures and animal models, allow for patient specificity in the model while accurately simulating in vivo tissue-like structures and functions in vitro. Compared to animal models, organoid cultures are easier to manipulate and conduct comprehensive biological studies on. As a result, organoid cultures have been used in many different contexts, such as cell therapy, tailored companion diagnostics, and drug discovery.

Dr. Upasana Y