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Organoids: Game changer

This is a brief article on current interesting research area that will revolutionize transplant field.  Organoids-  A self-organizing three-dimensional tissue known as an organoid is usually created from pluripotent, fetal, or adult stem cells. It replicates the essential biological, structural, and functional elements of an organ. Organoids are made up of cells that have been produced from tissue-derived cells (TDCs), induced pluripotent stem cells (iPSCs), differentiated cells, and cancer cells. Organoid cultures, in contrast to traditional 2D cultures and animal models, allow for patient specificity in the model while accurately simulating in vivo tissue-like structures and functions in vitro. Compared to animal models, organoid cultures are easier to manipulate and conduct comprehensive biological studies on. As a result, organoid cultures have been used in many different contexts, such as cell therapy, tailored companion diagnostics, and drug discovery. Dr. Upasana Y
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Contrast Agent correlation with phases for CT Abdomen

 Hello there, Iodine based low molecular weight correlation with phases in the CT abdomen protocol- I)Arterial phase hyperenhancement (APHE)= Injection Rate  II)Hepatic Parenchymal enhancement= Total Iodine dose Concentration Range -240-400 mgI/mL. >300 mg/mL yield better HCC detection and image quality Dr. Upasana Y
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Glimpse into my plan for "Last 18 Days to NEET PG"

 Hello believers at other end, If You have a plan and it is working well for you then no need to read it further. All the best and Happy studying. 18 days= 14 days(2 weeks) + 4 days( I would never count in last days )    I) 1st week = divide each day in three major slot and 2 minor slots By the end of 1st week I want to complete major and minor notes 6 minor + 4 major subject + PYQ +MCQ  of important topics + review images and volatile stuff. Seems daunting and impossible !? Say it to yourself "not daunting for me" Just 7 days and see the progress in the end. morning hours =  1 hour [ half hour pharma ( General,ANS,CVS,GIT ,RS+HORMONES,NEURO,Antimicrobial) 7 days) +  other half an hour ( Carb,lipid ,proteins,molecular,vitamins) *5days + last 2days when bio is completed I added PSM formulas for half an hour) 9am-12pm  = PYQ in form of GT on desktop like an exam ( And do it within 1 and half hour jaldi jaldi superficially) Review wrong ones .( Aim is to go through papers in sti
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#LMR Pathology summary sheet

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#LMR Blood supply of Internal capsule

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#LMR Approach to hyperbilirubinemia

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#LMR Fluids

Hello!  This post is regarding must know in fluids of choice topics . Remember about burns, DKA, CHPS (half strength NS  used), Amphotericin B and chloroquine.  Extra edge - sodium deficit (hyponatremia) fluid deficit (hyper)  RL avoided in liver failure  RL avoided in RF  Isotonic saline and RL do not contain glucose so preferred for diabetic patient  For acidosis Isolyte P, M, E RL For alkalosis Isolyte G.  Contraindication and indication of colloid. Did this much for exams. Baki you can add to the list. In case of amp B Prehydrated  with NS, reconstituted by distilled water. But during Amp B in diabetic( keep the check on hypokalemia) so DNS. In case of quinine we give with Glucose drip so that chances of hypoglycemia ca n be decreased. Hope it helps.  Upasana Y. 
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